INNOVATIVE PHARMACEUTICAL SOLUTIONS
FOR HEALTH & SAFETY

WORLDWIDE DEMAND MEETS SAFER ALTERNATIVE FOR OTC ANALGESICS

Products

U.S. CENSUS AND MARKET CONDITIONS

Aspirin is the most consumed medication in the world. It is used for a wide range of pain management purposes such as headache and also for prevention purposes such as stroke.

Following is a chart depicting worldwide analgesic market:

Total pain remedy sales in the US Market are approximately $5 billion. (AC Nielsen)


Aspirin is still the mostly widely used drug in the world - approximately 35,000 metric tons are produced and consumed annually, enough to make over 100 billion standard aspirin tablets every year, and its use is still growing. (Source: http://www.aspirin-foundation.com).

However, there are several known adverse effects with aspirin in many people. The main adverse effects of Aspirin are on the gastrointestinal system. Aspirin can cause nausea, vomiting, heartburn, and discomfort in the upper stomach. It may also cause ulcers in the stomach or duodenum (small intestine just beyond the stomach). Studies show that as many as 1 out of 5 cannot tolerate aspirin because of these GI side effects. Moreover, recent studies suggest negative effects of improper dosage strength, release, and coatings.

Cardiovascular disease is the leading cause of death worldwide, accounting for approximately one-third of all deaths. Aspirin is routinely recommended by physicians to prevent heart attack and for immediate treatment when it occurs. As a result, a frequent use of aspirin is prevention of heart disease (37.6%). Unfortunately, such routine use can lead to hemorrhaging and ulcers. Concern over such issues associated with taking traditional aspirin present a special opportunity for capturing market share for the Larasan product. Larasan's low dosage (81 mg) will provide effective around the clock delivery while virtually eliminating the negative side effects.

The pain and swelling associated with arthritis impacts juveniles, baby boomers, and senior citizens alike. This fact serves to increase the sales of a high dosage, safe and sustained action form aspirin, high dosage ibuprofen, and acetaminophen. It is approximated that the prescription market for arthritis exceeds $9.5 billion worldwide and the total arthritis medication market worldwide exceeds $20 billion.

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